The state of national innovation systems of Russia and EU countries in the context of these systems elements interaction with industrial enterprises is analyzed in the article. It is determined that it is necessary to significantly increase the role of enterprises in the national innovation system and the enterprises should keep to the proactive innovation policy for the long-term stable development of the Russian economics.

We suggest the method of assessment of the production and investment activity of the industrial enterprises which promotes their economically safe innovation development.

Dual nature of the entrepreneurship development is stipulated by its cost and usefulness. It is shown that the entrepreneurship efficiency should be assessed on the basis of its target direction and taking into account both cost and usefulness interests.

Enterprises have difficulties in financing the needs for the net circulating capital connected with operating activities during a crisis, as banks under the crisis conditions limit availability of loans. One of the solution is to decrease the needs for the net circulating capital. Factoring is a financial service application of which results in decreasing these needs. The restructured factoring combining the results of the debts factoring (shortening of the payment rotation cycle) and reverse factoring (extension of the commercial obligations performance cycle) is especially useful during a crisis. The article has the results of the studies confirming that the factoring ensures financial safety to enterprises more than a banking loan

The need to taking into account an environmental friendliness factor in the process of investment projects estimation is defined. The method of eco-economic estimation of the projects, which help to draw conclusions about the projects feasibility and to rank them according to the level of environmental and economic efficiency, is provided.
To objective justification for the investment decision, the projects efficiency criteria is suggested to calculate with using the elements of the fuzzy sets theory, through which many uncertainties factors may be formalized and correctly considered in the estimation process.